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Discovery may cure common cold
普通感冒有望治愈？
Sneezing, coughing, and sniffing. Welcome to winter and the common cold virus, a cure for which has eluded for years. But now a major breakthrough by scientists in Cambridge University brings that cure a step closer, as they've discovered a new way to help body's fight tough viruses.
打噴嚏，咳嗽，鼻塞。歡迎來到冬季，迎接感冒病毒。多年來，人們一直苦苦尋找感冒的治愈方法而無果。但是現在，劍橋大學的科學家取得了一項重大突破，使得找到感冒的治療方法更近了一步。他們發現了幫助身體抵抗這種頑固病毒的新方法。
Before we always thought of the antibodies which protects us from viruses only work outside cells. And once a virus has infected the cell, there is nothing your immune system can do, all it can do is killing infected cell. But what we discovered now is that actually antibodies are able to work inside the cell, where they triggers system of immunity that allows the cells to get rid of the viruses that already affecting them.
以前，我們總是認為保護我們免受病毒侵害的抗體只能作用于外部細胞。一旦病毒感染了細胞，免疫系統就無能為力了，只能殺死感染了的細胞。但是我們現在發現，實際上，抗體也能作用于內部細胞，觸發免疫系統允許細胞清除病毒。
And this is how it works. As the virus enters the cell it draws antibody shown here in yellow with it, inside a protein called TRIM21 recognizes the antibody as a foreign body and latches on to it. The TRIM21 protein that attracts powerful antiviral agents which degrades the virus, saving the cell. So by designing medicines to boost that protein, we could have a cure for the common cold.
這就是其作用機制。隨著病毒進入細胞，就會吸引抗體，也就是這里顯示黃色的部分，在內部，一種叫做TRIM21的蛋白質識別出這種抗體是外部物質，然后迅速抓住它。這種TRIM21蛋白吸引力有力的抗病毒劑，將病毒分解，拯救細胞。所以，通過設計增強這種蛋白質的藥物，我們或許能夠找到治療感冒的方法。
Every year almost all of us catch a cold, millions of us end up at the doctors' because of it, so any cure would be very welcome. But this new research could be revolutionary if it helps us to combat viruses in general.
每年，幾乎我們所有人都會感冒一次，數百萬人要到醫生那里尋找解決方法，所以，任何治療方法都會受歡迎。但是這項新的研究如果能幫我們抵抗病毒，將是革命性的。
Twice as many people die from viral illness than they do from cancer, even in this DNA age. So if we can understand what happens with the common cold, then use it as a model to try to beat and overcome other viruses that are more deadly, things like shingles, small pox and chicken pox, then you know, it's a really exciting prospect.
死于病毒性疾病的人數是死于癌癥人數的兩倍，即使在DNA時代。所以，如果我們能理解感冒的作用原理，然后建立模型，試圖抵抗和克服其他更加致命的病毒，比如帶狀皰疹，天花和水痘，前景將非常令人欣喜。
This is a historic discovery, the lab results are very encouraging, but it will be at least two to five years before any clinical trials can begin for any future treatments.
這是一項歷史性的發現，實驗室結果非常鼓舞人心，但是進行任何臨床試驗用于未來的研究至少還需要兩到五年的時間。
Sally Biddulph, by TV News.
Sally Biddulph，TV新聞。
