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It's an intervention study where again, in the healthy adults but at risk for Type 2 diabetes.
這是一項(xiàng)干預(yù)性研究對有患II型糖尿病的健康成年人來說
They compared sleep restriction to sleep extension in a randomized cross-over design and showed that in fact.
研究人員在隨機(jī)交叉試驗(yàn)中對睡眠限制和睡眠延時進(jìn)行了比較結(jié)果顯示
Sleep restriction was associated with reduced levels of activity so even though the maintenance of wakefulness has an energy cost.
睡眠限制與活動水平的降低有關(guān)因此 盡管保持蘇醒狀態(tài)會消耗能量
This stimulation of appetite is greater than the energy cost and then during the daytime.
但胃口調(diào)動起來后人們攝入的能量要高于所消耗的能量因此白天的時候
There's a tendency for the sleep-deprived individuals to expend less energy so that is kind of a Professor Ion left.
睡眠不足的個體傾向于消耗較少的能量這是艾伊恩教授留下的研究數(shù)據(jù)
So I'm just going to put that out there I think he would like this slide but the shift's illustrating the epidemic of obesity.
我把它放在這里我想他會感到高興的這個變化圖說明了
And the reduction in sleep duration and I just reviewed with you the laboratory evidence that kind of supports that link in the course of relationship.
肥胖癥和睡眠時間減少的變化趨勢我剛剛給大家講到了實(shí)驗(yàn)室的研究數(shù)據(jù)數(shù)據(jù)從某種程度上支持這種聯(lián)系的存在
Where those were all interventions studies there are large body of evidence or epidemiological evidence that I think we hear more about it today.
還提到這些都屬于干預(yù)性研究有大量證據(jù) 或大量流行病學(xué)證據(jù)證明我想我們今天已經(jīng)聽過了很多這方面的研究成果
But that's not what I want to continue to discuss now so now I want to discuss the risk of Type 2 diabetes and to just remind you that in this first study.
我不想就這個問題繼續(xù)講解下面我要講講II型糖尿病的風(fēng)險我想提醒大家的是 在第一項(xiàng)研究中
Dr. Spiegel performed this intravenous glucose tolerance test and just to remind the...how Type 2 diabetes evolves not in everybody.
斯彼格博士實(shí)施了靜脈內(nèi)葡萄糖耐受性測試我再給大家講講II型糖尿病是如何發(fā)展的不是每個人都會出現(xiàn)這個變化
In the majority of the subjects the tissues that need insulin to utilize glucose become less sensitive to insulin.
但大多數(shù)試驗(yàn)參與人都有需要胰島素去利用葡萄糖的器官變得對胰島素不再敏感
Also called "insulin resistant" so in order to achieve the same glucose metabolism the beta cells of the pancreas have to release more insulin.
這也被稱為"胰島素抗性"因此為了達(dá)到相同的葡萄糖代謝胰腺中的β細(xì)胞就需要釋放出更多的胰島素
