1.work at

從事于……，致力于……；鉆研

eg.Tom has been working at the subject for many years.
湯姆已經鉆研這門學科多年。

在……工作，在……任職

eg.Have you ever been working at the bank?
你在銀行工作過嗎?

2.hopelessadj.絕望的；不可救藥的

原文：It was hopeless to ask any more questions.

eg.We have to charge off the debt as hopeless.
我們只好把這筆債款作為無望收回而注銷。

eg.None of us are hopeless and we all have the power within ourselves to recover.
我們中沒有人是無望的，我們都可以從我們身上找到力量去復原。

eg.I'm hopeless at this myself, but I expect we'll all get better at this in the future.
我自己在這方面是不可救藥了，但我希望未來我們都能在這方面做得更好。