So there are some women
所以很多婦女的潮熱癥狀
who are severely affected by their hot flush
已經達到了非常嚴重的程度
But women who didn't complain at all about hot flushes
但雖然有的婦女自述沒有潮熱癥狀
had hot flushes during the night
但她們晚間確實也出現了潮熱
and didn't know it, didn't wake up
只是她們自己不知道 沒有醒過來而已
There were no differences in their sleep patterns either
她們的睡眠模式也沒有什么差別
no differences in any of their self-report
自述狀態(tài)也沒有差別
no differences in their amount of wake time
蘇醒時間長短也沒有差別
So again, all these objective measures
所以這些客觀測量結果
are showing the same thing
都得出了同樣的結論
So what we did was looked at sleep over time
從絕經前到絕經后的這段時間里
from premenopause to postmenopause
我們所關注的問題包括
and we looked all these factors
各個方面的因素
all the biological, psychological
我們每隔6個月
social issues in their lives every 6 months
就會對她們的生物 心理和社會指標進行評估
And we looked FSH level
我們會觀測試驗對象的FSH水平
and FSH follicle-stimulating hormone
也就是促卵泡激素水平
gets very high when you are menopausal
當女性進入絕經期時 FSH水平會升得很高
because you don't have estrogen to counter it
因為沒有雌激素去抑制FSH
so the FSH levels rise
所以FSH水平會變得很高
It's good indication of menopausal status
所以這是研究絕經狀態(tài)的一個很好的指標
We looked at diet, exercise
我們還會研究她們的飲食 鍛煉
a lot of diarrhea cause...
腹瀉狀況
I would like to hear your lecture from last week about diet
可惜我沒有參加上星期關于飲食的講座
We asked these women lots of questions about their diet
我們會提出很多關于飲食狀況的問題
and did body weight
詢問她們的體重變化情況
back bio-electrical impedance and so on
使用生物電阻測量法等
And we looked at stress
我們還會考察壓力
and family social relationships as they change over time
以及家庭社會關系的變化情況
We had quite a group of investigators on this team
我們的研究團隊中有很多的調查人員
Some of you might have actually been in this study
我們在舊金山灣區(qū)開展研究時
when we were in the San Francisco Bay Area
你們可能見過他們
They had to be community based sample of healthy women
她們都是社區(qū)中選出的健康女性
A lot of previous studies got women
過去的很多研究
from sleep disorder centers or menopause clinics
都是在睡眠障礙中心或治療絕經的診所進行的
where women are going because they have problems
那些地方的女性通常都有各種問題
We recruited from the community
這個研究的志愿者來自于社區(qū)
and they have to live here at least 20 years
她們在該社區(qū)至少居住了20年
speak English
能夠講英語
and be between 40 and 48
年齡在40到48歲之間
with regular cycles
生理周期正常
So what we found when we asked them
我們要求她們完成匹茲堡睡眠質量指數調查
on the Pittsburg Sleep Quality Index
也就是PSQI自述型文件調查
the PSQI self-report questionnaire, has about 21 items
這個問卷調查調查了21個項目
It's about 2 pages
有2頁
and it asked women about their sleep disruption
主要詢問女性的睡眠中斷情況
and sleep quality and quantity
以及睡眠質量的問題