So I'm gonna talk about the role of sleep deficiency
所以我打算講講睡眠缺乏
in predisposing to obesity
在肥胖癥易感性
and in that way to chronic health conditions across your lifespan
以及一生中所患慢性疾病中起到了什么作用
Then I'll touch on some mechanisms
然后我還會簡單講講這中間的機制
I'll talk about some of our sort of real life data
講講對青少年飲食和睡眠不足問題進行了研究后
on diet and sleep deprivation in teens
我們得到了哪些現實數據
I'm going to identify some paradoxes
我還要澄清一些矛盾
that I've seen in literature and certainly in our own data
很多研究文獻 當然也包括我們自己的研究
about age and gender
對年齡和性別差異都存在一些矛盾
and maybe challenge you to think about what
我還想讓大家思考
if they are real
如果這些矛盾確實存在
what they may be informing us
那么它們在生物學和發生機制上
about biology and mechanism
對我們有什么啟示
Then I'm going to also talk a little bit
接下來 我還要簡單講講
about some of the childhood risk factors
童年時期的那些風險因素
that might be a key link between sleep deficiency and obesity
可能成為睡眠缺乏和肥胖癥之間的關鍵連接
So I'd like you to start thinking too
首先 請大家思考
as we think about our lifespan approach
從人的全部生命期來看
is there a developmentally critical period
是否存在一個關鍵的發展期階段
where sleep deficiency may be particularly potent as a stimulus for obesity?
在這個階段中 睡眠缺乏成為了肥胖癥最重要的誘因?
Again,
這個問題
this is a little contrasted to our very first session that this morning
和我們今天早上聽到的報告剛好相反
we were told like
今天早上的報告告訴我們
let's look at the middle-aged people
看看中年人的情況吧
So many of you know this very old article now
你們很多人都知道這篇早期發表的文章
but what this really shows is
但這篇文章顯示
the importance of obesity in childhood about risk
童年時期肥胖的兒童
as a risk fact becoming obese as adults
成年后存在肥胖的風險