評論
打印
How many of you have your flu shot already this year?
你們有多少人今年已經注射過流感疫苗了?
Great
好極了
Did you get a good night sleep before you had a flu shot?
你們在注射之前睡了個好覺嗎?
Or after that flu shot?
注射之后睡個好覺了嗎?
There's a lot of data now that would indicate
現在有很多研究數據顯示
that if you are not getting sleep
如果你沒有睡好
a study of a healthy young man
對健康的年輕人的研究顯示
they have deprived them of sleep to 4 hours
如果他們連續4個晚上
a night for 4 nights
只睡4個小時
then gave them the flu shot
然后再接受流感疫苗注射
The other group sleeps normally
而另一組睡眠時間正常
and 10 days later
十天之后
they have much lower titer to their flu shot response rate
和正常睡眠的小組相比
than the young healthy men who got the normal sleep time
睡眠不足的小組血液中的流感抗體要低得多
This was in 2002
這是2002年的研究結果
It's been replicated in a fair number
這個試驗被重復了很多次
of other types of studies
選擇的疫苗各有不同
including hepatitis A vaccine
包括甲肝疫苗
Let me show you the results
我給大家看一看結果
These are a little easier to interpret
相對于其他疫苗或免疫方面的問題
than some of the other vaccination and immunization issues
這個數據要容易理解得多
but if both groups are sleeping fine
如果兩個小組的睡眠情況都正常
they get their flu shot
然后他們都接受了流感疫苗
the group that actually had good night sleep
那么接受疫苗注射之后
after the vaccine
睡了好覺的小組
had a much higher titer for Hep A vaccine
甲肝抗體的濃度
than the group that was left awake and kept awake
要高于注射流感疫苗之前
the whole night before their flu shot
整晚沒有睡覺的小組的濃度
So it's a very critical issue with cytokine metabolism
所以睡眠對細胞激素的代謝
going on in sleep
起到了非常重要的作用
and sleep is very important for immune function
睡眠對免疫功能至關重要
Now I've actually looked at sleep in pregnancy
我還研究了懷孕時的睡眠
This was...we should talk about publication problems
我要講講這方面論文的發表問題
because I was publishing on sleep and pregnancy
我本來打算發表一篇睡眠和懷孕的關系的文章
and I sent this to a couple of OB journals
我把文章投給了一份產科方面的學報
and they said
結果他們說
I'm sorry
對不起
we don't have anybody
我們這里沒有人能夠審閱
who can review any papers on sleep for women
女性睡眠問題的文章
Could you suggest them review yours
你能不能建議他們審閱
It was very difficult to get this published
所以文章很難發表
But we looked at women during their third trimester
我們研究了孕婦在臨產前3個星期
