Inflammatory response evolved to protect those living in the tenements at the time,
那時,炎癥反應發展成了對住在那些房子里的人的保護,
but it also had a trade-off later in life.
但是同樣也作出了壽命的交換。
An over-active immune system can end up attacking the body it is meant to protect.
一個過度活躍的免疫系統可以導致對它保護的身體的攻擊。
But of course, when they reach adult life or late adult life,
當然,當他們到成年或晚年時,
they've got more of a propensity for inflammatory-related diseases
就會得更多機會患上與炎癥有關的疾病,
like diabetes, heart disease and arthritis, which of course, are common in Glasgow.
比如糖尿病,心臟病和關節炎,這些都是格拉斯哥的常見病。
Even though their environment has changed and their lifestyle is healthy,
即使環境變化了,生活方式健康了,
Moira and Graham are still showing signs of a heightened immune response they inherited from their parents.
Moira和Graham還是顯示出他們從父母那里遺傳的高免疫反應。
The tenements themselves have gone,
他們住過的房子已經沒有了,
the overcrowding is a thing of the past
用具已經是過去的事情了,
and the city fathers have put in new housing where people are being moved to,
市政高官蓋起了新樓,人們搬了進去,
and it's improved dramatically their conditions,
條件得到明顯的改善,
but the legacies - through the processes we've described - are still there.
但是遺產——我們前面已經描述過了——還是存在。
The ill health still hangs over us to some extent
健康欠佳有時還高掛在我們頭上,
and we have to allow that to work out of the system.
我們必須解決這個問題。
So how can you make it to 101 without trying?
所以怎么能夠沒有煩惱活到101歲呢?
The answer is not only to look at your own life,
對于每個人的生活,沒有統一的答案,
but also to understand how your parents and grandparents lived theirs.
但是也要搞明白自己的父輩和祖輩是怎樣生活過來的。
Every community has a delicate relationship between past and present,
每個社區都存在過去和現在之間微妙的關聯,
between the environment our ancestors evolved to survive and the one we live in today.
存在著祖先生存發展的環境與我們現在生活的環境之間微妙的關聯。
Nowhere is the delicate nature of this relationship
這種關聯最微妙的本質
revealed more starkly than on the islands of Hawaii.
更多地暴露在夏威夷群島上。