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And one article that really stood out to me when I was just reading about this,
一篇文獻引起了我的注意，我讀這篇文獻，
trying to figure out why cancer doesn't go to skeletal muscle, was that it had reported 16 percent of micro-metastases to skeletal muscle upon autopsy. 16 percent!
試圖弄清楚為什么癌癥不會發生在骨骼肌，這篇文獻說，解剖時發現骨骼肌里有16%的微轉移，16%！
Meaning that there were these pinpoint tumors in skeletal muscle, but only 0.16 percent of actual metastases --
這意味著骨骼肌腫瘤中有小范圍的腫瘤，但只有0.16%的實際轉移。
suggesting that maybe skeletal muscle is able to control the angiogenesis, is able to control the tumors recruiting these blood vessels.
這表明骨骼肌也許是能夠控制血管生成過程，從而能夠控制腫瘤對血管的利用。
We use skeletal muscles so much. It's the one portion of our body -- our heart's always beating. We're always moving our muscles.
我們這么頻繁的使用骨骼肌。這是我們身體的一個部分，我們的心臟不停跳動。我們的肌肉一直處在活躍狀態。
Is it possible that muscle somehow intuitively knows that it needs this blood supply?
難道肌肉隱隱約約的“感覺”到它需要血液供應？
It needs to be constantly contracting, so therefore it's almost selfish. It's grabbing its blood vessels for itself.
它需要不停地收縮，因此，它幾乎是自私的,攫取血管為自己所用。
Therefore, when a tumor comes into skeletal muscle tissue, it can't get a blood supply, and can't grow.
因此，當腫瘤進入骨骼肌肉組織的時候，它不能獲得血液供應，也就不能生長。
So this suggests that maybe if there is an anti-angiogenic factor in skeletal muscle -- or perhaps even more, an angiogenic routing factor,
這也許表明，如果在骨骼肌中，有抗血管生成因子——或者更進一步，存在控制血管生成的因子，
so it can actually direct where the blood vessels grow -- this could be a potential future therapy for cancer.
可以調控血管生長的位置，這可能會成為另一種治療癌癥的方法。
And another thing that's really interesting is that there's this whole -- the way tumors move throughout the body,
另一件很有趣的事情是，腫瘤在全身的移動。
it's a very complex system -- and there's something called the chemokine network. And chemokines are essentially chemical attractants,
是一個非常復雜的系統，包含所謂的“趨化因子網絡”。趨化因子的本質是化學引誘物。
and they're the stop and go signals for cancer. So a tumor expresses chemokine receptors,
它們是癌癥的紅綠燈信號。因此，腫瘤表達為趨化因子受體。
and another organ -- a distant organ somewhere in the body -- will have the corresponding chemokines,
另一器官——一個離腫瘤一定距離的器官——將有相應的趨化因子。
and the tumor will see these chemokines and migrate towards it. Is it possible that skeletal muscle doesn't express this type of molecules?
腫瘤會看到這些趨化因子，并朝向它轉移，有沒有可能骨骼肌不表達這種類型的分子？
And the other really interesting thing is that when skeletal muscle -- there's been several reports that when skeletal muscle is injured, that's what correlates with metastases going to skeletal muscle.
還有一件事情很有趣，有幾個報告都提到，當骨骼肌損傷和腫瘤向骨骼肌的轉移密切相關。
