評論
打印
They took a step further and once again Dr. Wagner kind of gave us a preview of this
他們還進了一步，Wagner醫生之前也提到過
Now cultured in pools of serum that had been supplied by Dr. Hollis
這是在Hollis醫生所提供血清中的培養結果
One was an African-American pool; one was white pool
前兩個是非裔美國人和白人血清
And that's the amount of messenger RNA that was expressed in the African-American serum
這是非裔美國人血清中信使RNA表達的量
That's the amount that was expressed from the white serum
這是白人血清中的表達量
Now they said what's wrong with African-American serum?
他們問，非裔美國人血清是怎么回事？
Is there something genetically different about them?
其基因上是否有什么不同？
One thing we know is they don't have as much as vitamin D
非裔美國人沒有那么多維生素D
So let's add 25D to the serum and see what happens and lo and behold, they rescued it
加入一些25D到血清看看，結果很好
How much vitamin D are we talking about?
有多少維生素D
The African-American pool had 22 nmol which is 9 ng/ml
非裔美國人血清中是22納摩，也就是9納克/毫升
We would all agree by any standard that that's a clearly set normal value, whereas a white pool had 78
所有人都相信，不管怎么看這是他們的正常值而白人血清中是78
That's still not 80 that's surely not 100 nm or 40 ng but it was a lot better than the African-American
遠遠沒到100納摩或40納克，但比非裔美國人好多了
And that's what made a difference
這就是差別
and so these experiments showed that vitamin D is an essential mediator in the innate immune response definitively that serum 25D is the critical variable
這些實驗決定性地顯示，維生素D對免疫應答非常關鍵，血清25D是關鍵變量，
and at least some of the increased sensitivity to infection in vitamin D deficiency
至少維生素D缺乏者更容易患病
