評論
打印
And then what's important here is this analysis where glucose control which is really you know, how well the diabetes is controlled in patients.
這里很重要的一點是為了控制葡萄糖如果II型糖尿病患者要控制糖尿病
Who have Type 2 diabetes and take 1, 2, 3 drugs what is the impact of having OSA so it is compared to not having OSA.
他們需要服用1種 2種3種藥物那么睡眠性呼吸障礙有哪些影響呢因此我們將其與沒有睡眠性呼吸障礙
Having even mild OSA is associated with an increase in hemoglobin A1C of 1% I can tell you to get a decrease of 1% in your hemoglobin A1C.
中度睡眠性呼吸障礙進行了比較他們的血紅蛋白A1c會增加1%如果你患有糖尿病
If you are diabetic you have to take at least one drug and having severe OSA.
如果想讓血紅蛋白Aic降低1%你至少要服用一種藥物然后嚴重的睡眠性呼吸障礙的對象
Is compared to no OSA is associated with an increase in hemoglobin A1C by 2% which is really the equivalent of 2 to 3 drugs.
與無睡眠性呼吸障礙的對象進行了比較發現他們的血紅蛋白A1c升高了2%那么需要服用2到3種藥物才能達到這個效果
Now this is a cross-sectional analysis it doesn't have...doesn't tell us about the direction of causality.
這也是一個橫斷面研究并沒有告訴我們因果關系的發展方向
And clearly the major questions are whether effective treatment of OSA can improve glycemic control in patients with Type 2 diabetes.
顯然 主要的問題是對睡眠性呼吸障礙的有效治療能夠改變II型糖尿病患者的血糖
The data so far even though quite a number of groups are working on this remain somewhat inconclusive.
目前的數據顯示盡管有很多研究團隊致力于這個問題的研究但這個問題的答案還不確定
Not terribly encouraging one issue of course is compliance which is generally low.
而且也不是那么鼓舞人心當然其中一個問題是患者的依從性還比較低
And the second question would be does effective treatment of OSA if we had a treatment.
第二個問題是對睡眠性呼吸障礙的有效治療如果我們確實有治療方法
To which the subject would be really compliant would it delay the development of Type 2 diabetes or reduce the severity.
而且試驗對象也比較依從那么這種方法能否減緩II型糖尿病的發展或是減輕其嚴重程度?
And with these thoughts I will thank the numerous people who are working in this area with me.
我把這些問題留給大家我想感謝在這個領域和我共事的這些研究人員
