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The news that leptin made fat mice
瘦蛋白讓胖老鼠在幾周內瘦下來的新聞
thin in a matter of weeks had a massive popular appeal.
在廣大人群中引起了轟動
Researchers then looked at humans and discovered
研究人員隨后對人類進行了研究并發現
that the hormone leptin was a messenger molecule for us, too.
瘦蛋白激素對于我們也是一種信使分子
It travels up to the appetite
它能夠到達大腦中
control centre in the brain, the hypothalamus.
控制食欲的神經中樞 下丘腦
The hypothalamus acts like a thermostat.
下丘腦像自動恒溫器一樣工作
So if body fat increases,
如果體內脂肪增加
the leptin increases and appetite goes down.
瘦蛋白增加 食欲下降
When we lose fat,
如果脂肪減少
leptin signals become weaker and we eat.
瘦蛋白信號減弱 我們攝取食物
It's very clear now that there are several biological mechanisms
我們十分清楚 有數種生理機制
that determine how much
可以決定個體的體內
fat each individual maintains in their body,
需要保存多少脂肪
and any change, either by gaining
任何變化 無論是體重增加
weight or losing weight, is actively resisted.
或是體重減少 都可以得到有效地抑制
This is true for people who are
這對于略微超重
mildly overweight or people that are grossly obese.
或者是嚴重肥胖的人都是成立的
Cathy looks just great in hand-dyed,
凱西穿著這件手工染制的
original button-down front
紐扣領口設計的
in a full circle dress.
服飾看起來很好看
Beautiful, Cathy.
凱西 你真漂亮
So the hormone leptin maintains fat
因此瘦蛋白激素將脂肪維持在
at a steady level and makes dieting very difficult.
一個穩定的水平 讓節食變得十分困難
