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So, here's our strategy. First, we'll dose the cancer cell with siRNA, the gene blocker,
因此，我們的策略如下。首先，我們將siRNA--基因攔截者，用在癌細胞身上，
and silence those survival genes, and then we'll whop it with a chemo drug.
讓（癌細胞的）生存基因失效，然后我們再用化學(xué)藥品來對付癌細胞。
But how do we carry that out?
但如何實現(xiàn)呢？
Using molecular engineering, we can actually design a superweapon that can travel through the bloodstream.
答案是分子工程技術(shù)，我們可以設(shè)計一種超級武器，能在血液循環(huán)中存活下來。
It has to be tiny enough to get through the bloodstream, it's got to be small enough to penetrate the tumor tissue,
它必須足夠小，才可以進入血液循環(huán)，它必須足夠小，才可以穿過腫瘤組織，
and it's got to be tiny enough to be taken up inside the cancer cell.
它必須足夠小，才可以進入癌細胞內(nèi)部，
To do this job well, it has to be about one one-hundredth the size of a human hair.
要做到這一點，它的尺寸必須小到頭發(fā)的百分之一。
Let's take a closer look at how we can build this nanoparticle.
來仔細看一下我們是如何制造這種納米粒子的。
First, let's start with the nanoparticle core.
首先，我們要制造納米核。
It's a tiny capsule that contains the chemotherapy drug.
那是一顆小膠囊，內(nèi)含化學(xué)藥劑。
This is the poison that will actually end the tumor cell's life.
對腫瘤細胞而言是致命毒藥。
Around this core, we'll wrap a very thin, nanometers-thin blanket of siRNA. This is our gene blocker.
在內(nèi)核周圍，我們包上一層很厚的--當(dāng)然也就幾納米厚的siRNA。這是我們的基因攔截者。
Because siRNA is strongly negatively charged,
因為siRNA帶負(fù)電，
we can protect it with a nice, protective layer of positively charged polymer.
我們用一層堅固的，帶正電的聚合物來保護它。
The two oppositely charged molecules stick together through charge attraction,
這兩種帶有不同電荷的分子相互吸引，
and that provides us with a protective layer that prevents the siRNA from degrading in the bloodstream. We're almost done.
形成一層保護膜，防止siRNA在血液中被降解。別著急，我快說完了。
