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To finish I'll just show you the strategy.
最后，我只跟你們說一下戰(zhàn)略。
In this one I'm just using the interspecies molecule, but the logic is exactly the same.
在這里，我們只是使用跨菌種分子，但是思維邏輯是一模一樣的。
What you know is that when that bacterium gets into the animal, in this case, a mouse, it doesn't initiate virulence right away.
你們都知道，當(dāng)細菌進入動物體內(nèi)，以此為例，對這只老鼠，它并不會馬上啟動致病機制。
It gets in, it starts growing, it starts secreting its quorum sensing molecules.
它進入，開始增殖，開始分泌它的聚量感應(yīng)分子。
It recognizes when it has enough bacteria that now they're going to launch their attack, and the animal dies.
當(dāng)累積到足夠數(shù)量時，細菌能識別，并開始發(fā)起攻擊，然后老鼠就死了。
What we've been able to do is to give these virulent infections,
我們所做的是在致病感染的同時，
but we give them in conjunction with our anti-quorum sensing molecules
加入我們的“反聚量感應(yīng)分子”，
so these are molecules that look kind of like the real thing, but they're a little bit different which I've depicted on this slide.
也就是看起來很像真的“聚量感應(yīng)分子”的物質(zhì)，但是，正如同我在幻燈上指出的，它們之間有一點點不同。
What we now know is that if we treat the animal with a pathogenic bacterium -- a multi-drug-resistant pathogenic bacterium
我們現(xiàn)在發(fā)現(xiàn)，如果讓實驗動物感染一種具有多重耐藥性的致病細菌，
in the same time we give our anti-quorum sensing molecule, in fact, the animal lives.
但是同時，我們施予“反聚量感應(yīng)分子”治療，動物就能夠存活。
We think that this is the next generation of antibiotics and it's going to get us around, at least initially, this big problem of resistance.
我們認為這應(yīng)該是下一代的抗生素，它將能夠讓我們，至少在開始階段，解決耐藥性細菌的問題。
What I hope you think, is that bacteria can talk to each other, they use chemicals as their words,
我希望你們也能認為，細菌可以彼此交談，它們使用化學(xué)物質(zhì)當(dāng)作語言，
they have an incredibly complicated chemical lexicon that we're just now starting to learn about.
它們擁有極端復(fù)雜的化學(xué)語匯，我們現(xiàn)在才剛剛要開始學(xué)習(xí)這些語匯。
Of course what that allows bacteria to do is to be multicellular.
當(dāng)然，也因為這些語匯，使細菌得以變得像多細胞生物。
So in the spirit of TED they're doing things together because it makes a difference.
所以，就像TED的精神一樣，它們彼此合作，因為這樣才能有一番作為。
What happens is that bacteria have these collective behaviors
細菌因為有這些集體行為，
and they can carry out tasks that they could never accomplish if they simply acted as individuals.
所以可以執(zhí)行一些如果是單槍匹馬是永遠無法完成的任務(wù)。
