Mice were divided into four groups to examine different doses of the colour additive.
老鼠被分成四組以檢驗不同劑量的酒黃石效果
Tartrazine was given to a total of 60 mice
酒黃石分三種不同劑量攝入60只老鼠,
at three different doses plus one control group from where they were 5 weeks to 9 weeks old.
此外還有一對照組老鼠都是5周至9周大
The tartrazine was mixed and given as an oral tablet.
酒黃石與其他物質(zhì)想混制成口服藥片
After nine weeks researchers analyzed the mice's function and behaviour specifically
九周后研究者分析了老鼠的行為活動
looked at how long it would take for the mouse to turn over to its feet when it was placed on its back,
尤其觀察當(dāng)老鼠被躺著放置時,他們自己站起來所用的時長
how long it took for the mouse to bring its head up when placed upside down on an incline,
當(dāng)老鼠被傾斜著倒置時他們抬起頭所用時長
placing the mouse on a platform to determine its cliff avoidance
將其放在平板上觀察其懸崖回避能力
and how the mouse swam and behaved when placed in water
將其放入水中時它們的游泳與反應(yīng)狀態(tài)
and a test to determine the mouse's sense of smell by evaluating exploratory behaviour.
通過其探究行為探究老鼠的嗅覺
The results of the study determined Tartrazine did not affect the mice's food intake
研究結(jié)果顯示,酒黃石不會影響老鼠的進(jìn)食體重,
or body weight and the litter size of the offspring birth rate were also not affected.
而且老鼠每窩的仔畜數(shù)也沒有受到影響
It was determined that tartrazine affected the mice's exploratory behavoiur
據(jù)斷定。酒黃石影響老鼠的探究能力
but was most significantly seen in juvenile mice
但在幼鼠中表現(xiàn)明顯
which suggested that it would the most effect third generations.
且第三代幼鼠可能受到影響最大
Another finding was that tartrazine accelerated the mice's swimming ability especially with male mice.
另一發(fā)現(xiàn)是酒黃石會使老鼠游泳能力加強(qiáng),尤其是雄鼠
Overall the three doses that were used in the study
總之,研究中這三種不同劑量的攝入
did not have any negative effects on reproduction and only a few effects on behaviour.
沒有對其繁殖產(chǎn)生任何不良作用,僅對其行為產(chǎn)生一點(diǎn)影響
The dose level had the most significance in male mice which were the amounts that were greater than the recommended adequate intake.
如果攝入量比建議攝入量高的話,雄性老鼠受到的影響更大
Researchers determined that the levels of tartrazine humans consume would not produce any adverse effects.
研究者斷定,人類食用的酒石黃量不會造成任何不良影響
Another research article that was mentioned in the study above published in 2007 in the Regulatory toxicology and pharmacology journal
這項研究于2007年發(fā)表在雜志《管制毒理學(xué)與藥理學(xué)》上的另一篇文章
concluded that from prior research that tested tartrazine in mice for two years reported that
總結(jié)稱先前長達(dá)兩年的對老鼠食用酒石黃的探究顯示
the occurrence of tumours and disease are not related to tartrazine in the diet.
腫瘤的發(fā)現(xiàn)與相關(guān)疾病和飲食中的酒黃石沒有關(guān)系
Another finding from the study was that
這項研究中的另一個發(fā)現(xiàn)是
tartrazine was not absorbed by the body and was easily metabolized in the colon and excreted.
酒黃石不會被人體吸收,而是易在結(jié)腸處發(fā)生新陳代謝并被排出體外
Other various studies have also concluded that tartrazine has no carcinogenic effects
其他多項研究也得出結(jié)論,酒黃石沒有致癌作用
and does not affect development or reproductive behaviours.
不會影響機(jī)體發(fā)展和繁殖行為
Currently tartrazine is considered safe by the FDA.
目前食藥局認(rèn)為酒黃石是安全的