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科學美國人60秒:2018年諾貝爾生理學或醫學獎表彰對抗癌癥的免疫療法

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This is Scientific American — 60-Second Science. I'm Steve Mirsky.
"The Nobel Assembly at Karolinska Institute has today decided to award the 2018 Nobel Prize in Physiology or Medicine, jointly to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulation."
Thomas Perlmann, secretary of the Nobel Assembly shortly after 5:30 this morning Eastern time.
"James P. Allison was born in Alice, in Texas, in the United States. He performed his prize-winning studies at the University of California, Berkeley, and at Memorial Sloan Kettering Cancer Center in New York. He is now active at The University of Texas M. D. Anderson Cancer Center in Houston. Tasuku Honjo was born in Kyoto, in Japan. He performed his prize-winning studies at Kyoto University, where he is still active."

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Karolinska Institute immunologist Klas Kärre, a member of the Nobel Committee, explained the significance of the work of the new Nobel laureates:
"Allison's and Honjo's discoveries have added a new pillar in cancer therapy. It represents a completely new principle, because unlike the previous strategies it is not based on targeting the cancer cells, but rather the brakes, the checkpoints, of the host immune system. The seminal discoveries by the two laureates constitute a paradigmatic shift and a landmark in the fight against cancer."
For an in-depth listen about the 2018 Nobel Prize in Physiology or Medicine, look for the Scientific American Science Talk podcast later today.
For Scientific American — 60-Second Science. I'm Steve Mirsky.

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constitute ['kɔnstitju:t]

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vt. 構成,建立,任命

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inhibition [.inhi'biʃən]

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n. 禁止,禁制,壓抑

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jointly ['dʒɔ:intli]

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adv. 共同地,連帶地

 
memorial [mi'mɔ:riəl]

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adj. 紀念的,追悼的
n. 紀念碑(堂),

 
shift [ʃift]

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n. 交換,變化,移動,接班者
v. 更替,移

 
landmark ['lændmɑ:k]

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n. 陸標,地界標,里程碑,劃時代的事

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immune [i'mju:n]

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adj. 免除的,免疫的

 
previous ['pri:vjəs]

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adj. 在 ... 之前,先,前,以前的

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physiology [.fizi'ɔlədʒi]

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n. 生理學

 
pillar ['pilə]

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n. 柱子,支柱,核心(人物)
vt. 用柱支

 
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