評論
打印
A routine CAT scan turns up a suspicious spot.
一項常規CAT掃描發現了可疑陰影。
Is it a benign lump?
這是個良性腫塊?
Or a cancerous tumor?
還是惡性腫瘤?
In the case of lung spots, four out of five turn out to be harmless.
按照肺斑點所視,證明其十有八九是良性的。
Unfortunately, making that determination takes a long needle and a biopsy, which means a puncture wound in the chest and a risk of infection.
然而不幸的是,做出這個決定需要長針和活組織檢查,這意味著胸部刺傷及感染的風險。
Leroy Hood and colleagues at Seattle's Institute for Systems Biology have devised a painless blood test that could eliminate the need for most biopsies.
而西雅圖系統生物學研究所勒羅伊·霍德和同事們發明了一種無痛的血液測試,可以不需要進行大多數活檢。
They identified 371 proteins that coat lung tumors or leak out of them.
他們發現了371種覆蓋肺腫瘤或泄漏的蛋白質。
Then they looked at blood samples taken from people who had had lung biopsies.
然后他們觀察人肺活檢的血樣。
A pattern emerged: 13 proteins were significantly higher or lower in patients who had lung cancer than in those whose lumps were benign.
結果顯現:肺癌患者的13個蛋白質均明顯高于或低于比那些良性的腫塊。
The researchers tried the blood test on different patients, and found that when it gave an “all-clear” result, it was correct 90 percent of the time.
研究人員試圖對不同的患者進行血液測試,結果發現發現當給出“全部合格”的結果, 有90%是正確的。
The work appears in the journal Science Translational Medicine.
這項研究已經在《科學轉化醫學》雜志上發表。
Indi, a diagnostics maker, is commercializing the blood test.
而一家診斷制造商英蒂正試圖將這樣的血液測試商業化。
Hood says the same approach should work for almost any disease—which could make diagnostics much less prickly.
霍德表示同樣的方法應適用于幾乎可以使診斷更棘手的任何疾病。
