run sth
管理；經營:
Stop trying to run my life (= organize it) for me.
別老想操縱我的生活。

ratchet (sth) up
(使)逐漸小幅增長:
Overuse of credit cards has ratcheted up consumer debt to unacceptable levels.
濫用信用卡使消費債務逐漸增加到了難以接受的地步。

take charge
主管；掌管；照管；職責；責任:
He took charge of the farm after his father's death.
他在父親去世后掌管了農場。

set out
(懷著目標)開始工作,展開任務:
She set out to break the world record.
她一心努力要打破世界紀錄。

replace sb / sth (with / by sb / sth)
(用…)替換；(以…)接替:
It is not a good idea to miss meals and replace them with snacks.
不吃正餐,改吃點心,這不是什么好主意。

discredit sb/sth
敗壞…的名聲；使喪失信譽；使丟臉:
The photos were deliberately taken to discredit the President.
這些蓄意拍攝的照片旨在敗壞總統的名聲。