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科技動態:人造天然角膜甚至能制造淚水?

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Scientists in this laboratory in Sweden have made a medical breakthrough by cultivating artificial corneas they are able to store visions to millions of people in need of transplant in face of the risk of going blind. The biosynthetic cornea developed in Canada and Sweden looks like a contact lens. Eye surgeon May Griffith explains how it made.

瑞典一科學實驗室內的科學家們在人工角膜領域有了新突破。這將為幾百萬等待角膜移植,可能失明的患者帶來了光明。這種在加拿大和瑞典的人工合成角膜看上去就像隱形眼鏡一樣。眼科醫生May Griffith將向我們做詳細解釋。

"We started with the recombinant human collagen, so the first thing that was done was the scientist at Fibrogen, genetically engineered yeast. They took human DNA, put it into yeast cells, and got the yeast cells to produce this human protein. What we then did was take this protein chemically treated, put into molds and the result is a transparent contact lens looking like cornea. "

“我們從重組人體膠原蛋白開始,所以首先纖維蛋白原方面和基因工程方面的專家制作酵母,他們提取人類DNA,將DNA注入酵母細胞中,使酵母細胞生產人類蛋白質。我們接下來要做的就是將這些蛋白質進行化學處理,注入霉菌,結果就生成了看上去像隱形眼鏡的透明人工角膜。”

The procedure involves of removing the damage cornea which covers the iris of the people, and replace it with an artificial film-like one. The cornea itself is made from protein collagen, and reflects light allowing the retina to focus. The operation was carried out on 10 patients, and up until now, their sight has improved.

患者需要手術移除虹膜上受損的角膜,并換上人工角膜。這種新型的人工角膜由蛋白質組成,質地輕盈,使虹膜能夠自由聚焦。已經有10名患者接受了這種手術,截止到現在,他們的視力有了顯著提高。

This was a test designed primarily to look at the safety of implanting biomaterial into patients. But we were very surprised and very happy for the results we got. Because the results show that six out of ten patients could now see things about four times further away than they could before the operation. And when we put hard contact lens on all ten patients, the vision in all ten patients was improved.

這項實驗的初衷是檢驗向病人植入人造角膜的安全性。但結果讓我們驚訝并且十分興奮。結果顯示10名接受手術的患者中,六名患者可以看清以前視力所及距離的四倍以外的物體。而所有接受手術的10名患者的視力都有了很大改善。

The patients were monitored from 2 years, and doctor said 90% of the cases the tissue grew back completely joining together with the implant. Doctors said that there haven't been any adverse effects and the artificial cornea was mimicking a natural one with patients producing tears.

接受治療的患者將會被觀察兩年,醫生表示,90%的患者的眼部組織和植入的人造角膜完全愈合。醫生還說,人造角膜不僅沒有副作用,并且還能仿照天然角膜制造淚水。

Corneal disease affects millions of people around the world, and the number of transplants carried out limited due to a shortage of donors. The second and third phase of the test still needs to be carried out and medics say it will be another five years until the eye opening procedure will be performed at hospitals.

角膜類疾病困擾著全世界幾百萬人口,大批患者等待角膜移植,而捐獻者及其有限。人造角膜的第二第三階段實驗仍需實施,相關的醫學工作者表示,人造角膜應用于臨床還需要至少五年。

Basmah Fahim, Reuters.

Basmah Fahim,路透社消息。

recombinant n. 重組;[生]重組體

collagen n. (骨)膠原(蛋白);成膠質

yeast cells n.酵母細胞;酵母菌

iris n. 虹膜

注:本篇文章英文來自普特論壇,譯文屬可可英語原創,未經允許,請勿轉載。

重點單詞   查看全部解釋    
haven ['heivn]

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n. 港口,避難所,安息所 v. 安置 ... 于港中,

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protein ['prəuti:n]

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n. 蛋白質

 
iris ['airis]

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n. 虹膜,鳶尾屬植物,彩虹之女神

 
lens [lenz]

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n. 鏡頭,透鏡,(眼球的)水晶體
vt

 
yeast [ji:st]

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n. 酵母,發酵劑 vi. 發酵,起泡沫

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replace [ri(:)'pleis]

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vt. 取代,更換,將物品放回原處

 
adverse ['ædvə:s]

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adj. 不利的

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transparent [træns'perənt]

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adj. 透明的,明顯的,清晰的

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surgeon ['sə:dʒən]

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n. 外科醫生

 
breakthrough ['breik.θru:]

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n. 突破

 
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