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A new report suggests that breast-feeding, which has been associated with a reduced breast cancer risk, may have another benefit. In mothers who later develop breast cancer, breast-feeding may reduce the risk of cancer recurrence.
一份新的報(bào)告顯示，哺乳除了與較低的乳腺癌風(fēng)險(xiǎn)相關(guān)之外，可能還具有另一個(gè)好處。在后來罹患乳腺癌的母親中，哺乳或可降低癌癥復(fù)發(fā)的風(fēng)險(xiǎn)。
The study, in the July issue of The Journal of the National Cancer Institute, followed 1,636 breast cancer survivors. Researchers examined medical records and gathered data on whether mothers had ever breast-fed their children. They found 383 recurrences and 290 breast cancer deaths during an average nine years of follow-up after completion of treatment.
該研究發(fā)表在7月號(hào)的《國(guó)家癌癥研究所雜志》(Journal of the National Cancer Institute)上，共計(jì)隨訪了1636名乳腺癌幸存者。研究人員審查了她們的醫(yī)療記錄，并收集了關(guān)于其哺乳史的數(shù)據(jù)。他們發(fā)現(xiàn)，在治療結(jié)束后的隨訪期間（中位時(shí)間為九年），出現(xiàn)了383例復(fù)發(fā)，290人因乳腺癌死亡。
After controlling for age, smoking, education, race, type of therapy and other factors, they found that compared with women who had never breast-fed, any breast-feeding was associated with a 30 percent reduced risk of recurrence, and breast-feeding for more than six months was associated with a 37 percent reduced risk. There were similar risk reductions for breast cancer deaths.
在對(duì)年齡、吸煙史、教育狀況、種族、接受治療的類型和其他因素進(jìn)行校正后，研究人員發(fā)現(xiàn)，與從未哺乳過的女性相比，哺乳史與復(fù)發(fā)風(fēng)險(xiǎn)降低30%相關(guān)，哺乳期超過六個(gè)月與復(fù)發(fā)風(fēng)險(xiǎn)降低37%相關(guān)。在因乳腺癌死亡的風(fēng)險(xiǎn)方面也可見類似的降低。
“Breast-feeding is a good thing for the baby, and there are additional benefits for the mom that this study suggests,” said the lead author, Marilyn L. Kwan, a research scientist at Kaiser Permanente in Oakland, Calif. “This contributes to information already available in making a personal decision about whether or not to breast-feed.”
“母乳喂養(yǎng)對(duì)嬰兒有益，而該研究表明此舉也能給母親帶來額外的好處，”該研究的主要作者，凱薩醫(yī)療機(jī)構(gòu)（Kaiser Permanente，位于加利福尼亞州奧克蘭市）的科學(xué)家瑪麗蓮·L·關(guān)(Marilyn L. Kwan)說?！斑@一研究結(jié)果為母親決策自己是否要進(jìn)行哺乳提供了更多有益的信息?！?/p>
The risk reductions were particularly apparent in estrogen-receptor positive cancers, the most common type, but were not significant for women with HER2 positive tumors. Breast-feeding leads to certain molecular changes in breast cells, which may help explain the effect.
這種風(fēng)險(xiǎn)的降低在最常見的一類乳腺癌——雌激素受體陽(yáng)性癌癥中尤其明顯，但在HER2（人類表皮生長(zhǎng)因子受體2）陽(yáng)性腫瘤患者中并不顯著。哺乳可引起乳腺細(xì)胞中的一些特定的分子改變，這可能有助于解釋上述影響。
