評(píng)論
打印
An honest error has led to promising research into the development of species-specific insecticides.
一個(gè)誠(chéng)實(shí)的錯(cuò)誤已經(jīng)引領(lǐng)研究人員對(duì)于特有殺蟲(chóng)劑開(kāi)展了有最具潛力的研究。
The account is in the journal Nature Communications.
這項(xiàng)研究已經(jīng)在《自然通訊》雜志上發(fā)表。
A team of Johns Hopkins scientists study sodium channels responsible for electrical signaling in nerve cells from humans and from cockroaches.
約翰霍普金斯大學(xué)的一個(gè)科學(xué)家研究小組致力于人類和蟑螂神經(jīng)細(xì)胞里負(fù)責(zé)電氣信號(hào)鈉離子通道的研究。
Spider venom protein messes with these sodium channels—that’s why venom is dangerous.
研究發(fā)現(xiàn)蜘蛛毒液蛋白可以干擾這條彼此間的通道—這就說(shuō)明毒液極具危險(xiǎn)性的原因。
So the researchers use spider venom protein to disrupt the channels and thus clarify exactly how the channels function.
因此研究人員用蜘蛛毒液干擾鈉離子通道，因此恰好闡明了通道運(yùn)作的原理。
The researchers recently asked for venom protein samples from Australian collaborators.
研究人員最近從澳大利亞合作研究人員那里找來(lái)毒液蛋白樣品。
And the Aussies accidentally included a spider venom protein that has no effect on humans or American cockroaches.
然而他們意外發(fā)現(xiàn)這些樣本中存在一個(gè)對(duì)人類和美國(guó)蟑螂沒(méi)有影響的蜘蛛毒液蛋白樣品。
In their tests, the Hopkins researchers found when sodium channels from German cockroaches were exposed to the mistakenly included sample, their activity skyrocketed, enough to cause death-inducing seizures.
在測(cè)試中，霍普金斯大學(xué)研究人員發(fā)現(xiàn)當(dāng)?shù)聡?guó)蟑螂神經(jīng)細(xì)胞里的鈉離子通道接觸這一錯(cuò)誤的特別樣本時(shí)，它們呈現(xiàn)情緒高漲，行為活躍，引發(fā)痙攣，甚至死亡的表現(xiàn)。
Intrigued that the American roach sodium channel laughed off the venom that would kill the German roach, the scientists found a key region on the two species'channels that differed by only two amino acids.
對(duì)美國(guó)蟑螂毫無(wú)影響力的毒液卻可以殺死德國(guó)蟑螂。研究人員于此發(fā)現(xiàn)關(guān)鍵這兩個(gè)物種通道有兩個(gè)不同的氨基酸。
The scientists say the information could help with the creation of insecticides that target one harmful insect species without hurting beneficial ones, like bees.
科學(xué)家稱這一信息可以有助于針對(duì)害蟲(chóng)，而不傷害像蜜蜂這樣有益昆蟲(chóng)殺蟲(chóng)劑的制造。
As the study authors note: The more specific a toxin's target, the less dangerous it is for everything else."
就像這項(xiàng)研究的作者所坦言的：殺蟲(chóng)劑針對(duì)的目標(biāo)越具體，對(duì)別的物種的傷害就越小。
