評論
打印
Cathy repeats the memory test with a squad of 12 mice...
凱西在這十二只老鼠身上不斷重復這個記憶測試...
Before moving on to a second group of mice who received THC when they were slightly older, equivalent to teenagers aged 15 and over.
然后再對另一組老鼠進行測試。它們使用大麻的時間較晚，相當于人類15歲以上。
And straight there.
一下就到了。
That's right. So you see a much straighter, a more directed action to the pool, and he found it much quicker.
是的，這只老鼠找到平臺，游的路線更短，花的時間更快。
Once more, twelve mice are tested before Cathy compares the results of the two groups against a control group.
凱西又對另外十二只老鼠進行了同樣的測試。然后把兩組結果和控制組比較。
So this is the track data that we have from the computer system that we use, it's able to give us really accurate recording and measures of...
這些是老鼠游過的軌跡，是我們使用電腦系統記錄下來的。它幫助我們精確地記錄和測量...
not just the time it takes for the mice to reach the platform, but also how far they've swam, the distance they've swam.
不僅老鼠到達平臺使用的時間，還有它們游過的速度和距離。
So the first mice we have here, these are the black mice that received THC when they were very young adolescents,
這是測試的第一只老鼠，這些黑老鼠都是在年幼時就使用了大麻。
And if you look at the track, they're really swimming all over the pool really,
如果你看一下軌跡的話，你會看到它們幾乎遍布了整個水池，
not in a very straight pattern, and taking a long time to reach the location.
蜿蜒曲折，使用的時間也很長。
So if we now compare to the mice who received the THC when they were teenagers or young adults, you can see they really have learnt the location of the platform.
如果我們現在把它們和年長點才使用大麻的老鼠比較，你能看到后者已經記住了平臺的位置。
So clearly, giving THC when you're an older age doesn't seem to cause an impairment.
所以很明顯，如果年紀稍長些再使用大麻，可能不會造成損害。
And can you quantify the difference between the two?
你能說一下兩者有多大的區別嗎？
We do find a very large significant difference, as much as 25% deficit in the THC-treated young adolescent mice,
我們發現一個非常重大的差異，大約有1/4的使用THC的年幼老鼠會出現問題，所以我們非常確定給年幼的孩子THC，會對他們成年后的記憶產生巨大的影響。
so we really are fairly sure that there's a strong impact in giving THC to young adolescents.
因此我們非常確定，若孩子在年幼時接觸大麻，會產生重大的影響。
There's a lasting effect on their memory performance when they're adult.
會對他們成年后的記憶力產生持續的作用。
Could you translate that to human development?
你能不能說一下它對人類成長的影響？
That's right. We think that would indicate the vulnerable group are children under 15 receiving high doses or concentrations of THC repeatedly.
我們認為這些實驗對象能代表15歲以下的，長期吸入大劑量、高純度THC的孩子。
It's a worrying trend, because the number of children who are now taking cannabis is really on the rise.
現在，使用大麻的小孩的人數正在不斷增加，這是一個讓人十分憂心的趨勢。
So we know that in the UK at least, 40% of 15-year-olds have tried cannabis already.
據我們所知，僅在英國，40%的15歲以下的小孩曾吸過大麻。
And this is really at the point at which they might be developmentally vulnerable to the effects of THC.
而這時正是他們會受到THC影響的成長期。
Cathy's research implies that just a few years can make a critical difference to how cannabis affects your brain.
凱西的研究表明，僅僅幾年時間的差異，大麻對你腦部的影響就大不相同。
But for schizophrenia to develop is rare.
但精神分裂產生是很罕見的。
The likelihood of developing schizophrenia in your lifetime is 1%.
你一生中患上精神分裂的可能性只有1%。
Occasional cannabis use can raise this to 2% while heavy use might raise the lifetime risk to 6%.
偶爾使用大麻會提高到2%，而大量使用會提高到6%。
