1.lead to 導致；通向

This can lead to significant distress, but have no fear!
這可能導致巨大的壓力，但是不要害怕！

I believe that his friends, above all Halifax, came to the conclusion that he must be rooted out of the life he was leading at Trinity which must soon lead to decay of mind and health.
我相信他的朋友們，首先是哈利法克斯得出這樣的結論：他必須從在三一學院沿循的生活中拔出腳來，否則它必定很快會導致精神和健康的衰落y^jLdnlpCH||JKqzEDM。

2.open up 打開；開發

The doctor opened up his stomach to get at the source of the trouble.
醫生給他的胃開了刀，以便找出病根P@b^Ry9])lZo7,[jm。

He decided to open up a business in the city.
他決定在城里開一家商店JYTFUi72SLF。