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60秒科學(xué):想看工作中的腦細(xì)胞嗎?

時間:2010-05-07 11:21:45 來源:scientificamerican 編輯:scientificamerican  每天三分鐘英語輕松學(xué)

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神經(jīng)科學(xué)家的一大夢想,就是觀看工作中的腦細(xì)胞。如今,新的研究發(fā)現(xiàn)一種工具,通過它可以觀測到對刺激產(chǎn)生反應(yīng)的神經(jīng)元。

The big dream for neuroscientists is to be able to watch our brain cells in action, in real time

Well, new research has maybe found the most promising tool yet—a technique to watch individual neurons light up in response to a stimulus, like flipping on a light switch.

Scientists at the Max Planck Institute inserted a light-sensitive protein into a lab mouse. When a neuron fires, calcium ions flood through special cell channels. And when this light-sensitive protein binds to calcium, it radiates yellow light. So when the neuron fires it glows yellow.

When scientists shot a puff of air at the mouse’s whiskers, the brain cells in the sensory areas of the cortex glowed yellow. They watch this via thin glass fibers inserted into that brain region.

With this technique scientists now have a way to watch single cell activity in many different regions of the brain at once.

The hope is to investigate how the brain forms and loses neural connections during life experiences and when suffering from illnesses such as Alzheimer’s, Parkinson’s and schizophrenia.

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